Drug interactions
Quinupristin / dalfopristin + Tinidazole
Severity: Minor
Quinupristin / dalfopristin and Tinidazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinupristin/dalfopristin inhibits CYP3A4 and may raise concentrations of tinidazole. The effect is likely modest for a standard short course.
What this interaction means in plain words
Quinupristin / dalfopristin and Tinidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Quinupristin/dalfopristin inhibits CYP3A4, reducing tinidazole metabolism.
What to do
No routine adjustment is needed. Monitor for tinidazole adverse effects such as nausea or neurological symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tinidazole
- Disulfiram + Tinidazole Contraindicated
- Ethanol + Tinidazole Major
- Fexinidazole + Tinidazole Major
- Lopinavir + Tinidazole Major
- Nilotinib + Tinidazole Major
- Ritonavir + Tinidazole Major
Frequently asked questions
Can I take Quinupristin / dalfopristin with Tinidazole?
MediHelp rates the interaction as minor. Quinupristin / dalfopristin and Tinidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quinupristin/dalfopristin inhibits CYP3A4 and may raise concentrations of tinidazole. The effect is likely modest for a standard short course.
How serious is the interaction between Quinupristin / dalfopristin and Tinidazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor for tinidazole adverse effects such as nausea or neurological symptoms.
What other medicines interact with Tinidazole?
MediHelp also lists interactions of Tinidazole with, for example, Disulfiram, Ethanol, Fexinidazole. The full list is on the Tinidazole page.
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