Drug interactions
Rabies vaccine chick embryo cell derived + Ustekinumab
Severity: Moderate
Rabies vaccine chick embryo cell derived and Ustekinumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ustekinumab may reduce the antibody response to inactivated rabies vaccine. This is relevant for post-exposure or pre-travel prophylaxis.
What this interaction means in plain words
Rabies vaccine chick embryo cell derived and Ustekinumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Immunomodulation through IL-12/23 inhibition may reduce vaccine immune response.
What to do
Give rabies vaccine as indicated, and check rabies neutralizing antibody titers after vaccination. Post-exposure care must not be delayed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ustekinumab
- Bcg vaccine live + Ustekinumab Contraindicated
- Typhoid vaccine live + Ustekinumab Contraindicated
- Adalimumab + Ustekinumab Major
- Adenovirus types 4 and 7 live + Ustekinumab Major
- Alefacept + Ustekinumab Major
- Anakinra + Ustekinumab Major
Frequently asked questions
Can I take Rabies vaccine chick embryo cell derived with Ustekinumab?
MediHelp rates the interaction as moderate. Rabies vaccine chick embryo cell derived and Ustekinumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ustekinumab may reduce the antibody response to inactivated rabies vaccine. This is relevant for post-exposure or pre-travel prophylaxis.
How serious is the interaction between Rabies vaccine chick embryo cell derived and Ustekinumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give rabies vaccine as indicated, and check rabies neutralizing antibody titers after vaccination. Post-exposure care must not be delayed.
What other medicines interact with Ustekinumab?
MediHelp also lists interactions of Ustekinumab with, for example, Bcg vaccine live, Typhoid vaccine live, Adalimumab. The full list is on the Ustekinumab page.
Full monographs, dosing and an interaction checker in the MediHelp app
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