Drug interactions
Rasagiline + Somatrogon
Severity: Minor
Rasagiline and Somatrogon: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase CYP450 activity, including CYP1A2, which clears rasagiline. Rasagiline exposure could fall slightly, though the clinical effect is probably small.
What this interaction means in plain words
Rasagiline and Somatrogon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Rasagiline belongs to Central Nervous System; Somatrogon belongs to Endocrine.
Why it happens
Growth hormone may induce CYP1A2-mediated metabolism of rasagiline.
What to do
Monitor motor symptom control when growth hormone therapy is started or changed. Adjust the rasagiline dose only if efficacy is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rasagiline
- Atomoxetine + Rasagiline Contraindicated
- Brimonidine + Rasagiline Contraindicated
- Bupropion-naltrexone + Rasagiline Contraindicated
- Bupropion + Rasagiline Contraindicated
- Clomipramine + Rasagiline Contraindicated
- Desvenlafaxine + Rasagiline Contraindicated
Other interactions of Somatrogon
- Alogliptin-metformin + Somatrogon Moderate
- Alogliptin-pioglitazone + Somatrogon Moderate
- Alogliptin + Somatrogon Moderate
- Canagliflozin-metformin + Somatrogon Moderate
- Chlorpropamide + Somatrogon Moderate
- Cyclosporin + Somatrogon Moderate
Frequently asked questions
Can I take Rasagiline with Somatrogon?
MediHelp rates the interaction as minor. Rasagiline and Somatrogon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase CYP450 activity, including CYP1A2, which clears rasagiline. Rasagiline exposure could fall slightly, though the clinical effect is probably small.
How serious is the interaction between Rasagiline and Somatrogon?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor motor symptom control when growth hormone therapy is started or changed. Adjust the rasagiline dose only if efficacy is lost.
What other medicines interact with Rasagiline?
MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.
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