Drug interactions
Repaglinide + Shark cartilage
Severity: Minor
Repaglinide and Shark cartilage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shark cartilage has been proposed to have some glucose-lowering activity, which could add to repaglinide. The evidence is theoretical and clinical significance is unclear.
What this interaction means in plain words
Repaglinide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive glucose-lowering effect; the mechanism is not well established.
What to do
Check blood glucose more often if the patient starts taking shark cartilage supplements. Adjust repaglinide only if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Repaglinide
- Gemfibrozil + Repaglinide Contraindicated
- Clarithromycin + Repaglinide Major
- Clopidogrel + Repaglinide Major
- Cobicistat + Repaglinide Major
- Cyclosporine + Repaglinide Major
- Cyclosporin + Repaglinide Major
Frequently asked questions
Can I take Repaglinide with Shark cartilage?
MediHelp rates the interaction as minor. Repaglinide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage has been proposed to have some glucose-lowering activity, which could add to repaglinide. The evidence is theoretical and clinical significance is unclear.
How serious is the interaction between Repaglinide and Shark cartilage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more often if the patient starts taking shark cartilage supplements. Adjust repaglinide only if hypoglycemia occurs.
What other medicines interact with Repaglinide?
MediHelp also lists interactions of Repaglinide with, for example, Gemfibrozil, Clarithromycin, Clopidogrel. The full list is on the Repaglinide page.
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