Drug interactions
Repaglinide + Triamcinolone acetonide injectable
Severity: Moderate
Repaglinide and Triamcinolone acetonide injectable: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Injected triamcinolone can raise blood glucose and counteract repaglinide. Hyperglycemia may last days to weeks after a depot injection.
What this interaction means in plain words
Repaglinide and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Corticosteroids increase hepatic gluconeogenesis and insulin resistance, opposing the antidiabetic effect.
What to do
Monitor blood glucose for several days to weeks after injection and increase antidiabetic therapy if needed. Reduce the dose again as steroid effect wanes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Repaglinide
- Gemfibrozil + Repaglinide Contraindicated
- Clarithromycin + Repaglinide Major
- Clopidogrel + Repaglinide Major
- Cobicistat + Repaglinide Major
- Cyclosporine + Repaglinide Major
- Cyclosporin + Repaglinide Major
Frequently asked questions
Can I take Repaglinide with Triamcinolone acetonide injectable?
MediHelp rates the interaction as moderate. Repaglinide and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Injected triamcinolone can raise blood glucose and counteract repaglinide. Hyperglycemia may last days to weeks after a depot injection.
How serious is the interaction between Repaglinide and Triamcinolone acetonide injectable?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose for several days to weeks after injection and increase antidiabetic therapy if needed. Reduce the dose again as steroid effect wanes.
What other medicines interact with Repaglinide?
MediHelp also lists interactions of Repaglinide with, for example, Gemfibrozil, Clarithromycin, Clopidogrel. The full list is on the Repaglinide page.
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