Drug interactions
Repaglinide + Vanadium
Severity: Minor
Repaglinide and Vanadium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vanadium compounds have insulin-mimetic properties and may lower blood glucose. Combined with repaglinide, additive hypoglycemia is possible, although clinical evidence is limited.
What this interaction means in plain words
Repaglinide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Insulin-mimetic and insulin-sensitizing action of vanadium adds to the secretagogue effect of repaglinide.
What to do
Monitor blood glucose when vanadium supplements are used and reduce the repaglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Repaglinide
- Gemfibrozil + Repaglinide Contraindicated
- Clarithromycin + Repaglinide Major
- Clopidogrel + Repaglinide Major
- Cobicistat + Repaglinide Major
- Cyclosporine + Repaglinide Major
- Cyclosporin + Repaglinide Major
Frequently asked questions
Can I take Repaglinide with Vanadium?
MediHelp rates the interaction as minor. Repaglinide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vanadium compounds have insulin-mimetic properties and may lower blood glucose. Combined with repaglinide, additive hypoglycemia is possible, although clinical evidence is limited.
How serious is the interaction between Repaglinide and Vanadium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when vanadium supplements are used and reduce the repaglinide dose if hypoglycemia occurs.
What other medicines interact with Repaglinide?
MediHelp also lists interactions of Repaglinide with, for example, Gemfibrozil, Clarithromycin, Clopidogrel. The full list is on the Repaglinide page.
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