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Drug interactions

Repaglinide + Vanadium

Severity: Minor

Repaglinide and Vanadium: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Vanadium compounds have insulin-mimetic properties and may lower blood glucose. Combined with repaglinide, additive hypoglycemia is possible, although clinical evidence is limited.

What this interaction means in plain words

Repaglinide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Insulin-mimetic and insulin-sensitizing action of vanadium adds to the secretagogue effect of repaglinide.

What to do

Monitor blood glucose when vanadium supplements are used and reduce the repaglinide dose if hypoglycemia occurs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Repaglinide with Vanadium?

MediHelp rates the interaction as minor. Repaglinide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vanadium compounds have insulin-mimetic properties and may lower blood glucose. Combined with repaglinide, additive hypoglycemia is possible, although clinical evidence is limited.

How serious is the interaction between Repaglinide and Vanadium?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when vanadium supplements are used and reduce the repaglinide dose if hypoglycemia occurs.

What other medicines interact with Repaglinide?

MediHelp also lists interactions of Repaglinide with, for example, Gemfibrozil, Clarithromycin, Clopidogrel. The full list is on the Repaglinide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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