Drug interactions

rifampin + ticagrelor

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Major · Evidence level: High

↓ ticagrelor → thrombosis risk.

Mechanism of action

CYP3A induction.

Clinical management

Avoid combination.

Drug reference

References

Frequently asked questions

Can I take rifampin with ticagrelor?

The interaction is rated: Major. ↓ ticagrelor → thrombosis risk.

How serious is the interaction between rifampin and ticagrelor?

The interaction is rated: Major. Evidence level: High.

How is the interaction between rifampin and ticagrelor managed?

Avoid combination.

Why do rifampin and ticagrelor interact?

CYP3A induction.

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