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Drug interactions

Sage + Saxagliptin-metformin

Severity: Minor

Sage and Saxagliptin-metformin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Sage extracts have shown glucose-lowering activity in small studies, so they may add to antidiabetic drugs. The evidence is limited and hypoglycemia is unlikely.

What this interaction means in plain words

Sage and Saxagliptin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive glucose-lowering effect; the mechanism is not well established.

What to do

Monitor blood glucose if sage supplements are used regularly. Adjust therapy only if readings fall.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Sage with Saxagliptin-metformin?

MediHelp rates the interaction as minor. Sage and Saxagliptin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage extracts have shown glucose-lowering activity in small studies, so they may add to antidiabetic drugs. The evidence is limited and hypoglycemia is unlikely.

How serious is the interaction between Sage and Saxagliptin-metformin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if sage supplements are used regularly. Adjust therapy only if readings fall.

What other medicines interact with Saxagliptin-metformin?

MediHelp also lists interactions of Saxagliptin-metformin with, for example, Atazanavir, Clozapine, Contrast media. The full list is on the Saxagliptin-metformin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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