Drug interactions
Sage + Secobarbital
Severity: Minor
Sage and Secobarbital: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Some sage preparations are traditionally considered to have mild sedative properties, so they might add to the sedation produced by secobarbital. The clinical impact is probably small and the evidence is largely theoretical.
What this interaction means in plain words
Sage and Secobarbital have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depressant effects; the mechanism is not firmly established.
What to do
Advise patients to be alert for increased drowsiness and to avoid driving until the response is known. Reduce or stop the herbal product if excess sedation occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Secobarbital
- Calcium / magnesium / potassium / sodium oxybates + Secobarbital Contraindicated
- Doravirine + Secobarbital Contraindicated
- Elbasvir / grazoprevir + Secobarbital Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Secobarbital Contraindicated
- Isavuconazonium + Secobarbital Contraindicated
- Lonafarnib + Secobarbital Contraindicated
Frequently asked questions
Can I take Sage with Secobarbital?
MediHelp rates the interaction as minor. Sage and Secobarbital have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Some sage preparations are traditionally considered to have mild sedative properties, so they might add to the sedation produced by secobarbital. The clinical impact is probably small and the evidence is largely theoretical.
How serious is the interaction between Sage and Secobarbital?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to be alert for increased drowsiness and to avoid driving until the response is known. Reduce or stop the herbal product if excess sedation occurs.
What other medicines interact with Secobarbital?
MediHelp also lists interactions of Secobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Secobarbital page.
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