Drug interactions
Sage + Sitagliptin
Severity: Minor
Sage and Sitagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage preparations have reported blood glucose lowering activity in small studies. Combined with sitagliptin, glucose-lowering could be modestly additive, though the clinical significance is uncertain.
What this interaction means in plain words
Sage and Sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive glucose-lowering effect; the mechanism of sage's effect is not well established.
What to do
Monitor blood glucose if the patient uses sage supplements regularly or in medicinal amounts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sitagliptin
- Albiglutide + Sitagliptin Moderate
- Amlodipine-benazepril + Sitagliptin Moderate
- Aripiprazole + Sitagliptin Moderate
- Asenapine + Sitagliptin Moderate
- Benazepril + Sitagliptin Moderate
- Captopril-hydrochlorothiazide + Sitagliptin Moderate
Frequently asked questions
Can I take Sage with Sitagliptin?
MediHelp rates the interaction as minor. Sage and Sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage preparations have reported blood glucose lowering activity in small studies. Combined with sitagliptin, glucose-lowering could be modestly additive, though the clinical significance is uncertain.
How serious is the interaction between Sage and Sitagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if the patient uses sage supplements regularly or in medicinal amounts.
What other medicines interact with Sitagliptin?
MediHelp also lists interactions of Sitagliptin with, for example, Albiglutide, Amlodipine-benazepril, Aripiprazole. The full list is on the Sitagliptin page.
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