Drug interactions
Sage + Thioridazine
Severity: Minor
Sage and Thioridazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thioridazine is strongly sedating. Sage is a herbal product with a theoretical sedative effect, so additive drowsiness is conceivable but poorly documented.
What this interaction means in plain words
Sage and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; the mechanism is not well established for sage.
What to do
Advise patients to watch for excess drowsiness and avoid driving if impaired. Discourage concentrated sage supplements during thioridazine therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Frequently asked questions
Can I take Sage with Thioridazine?
MediHelp rates the interaction as minor. Sage and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thioridazine is strongly sedating. Sage is a herbal product with a theoretical sedative effect, so additive drowsiness is conceivable but poorly documented.
How serious is the interaction between Sage and Thioridazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excess drowsiness and avoid driving if impaired. Discourage concentrated sage supplements during thioridazine therapy.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
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