Drug interactions
Sage + Ziprasidone
Severity: Minor
Sage and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ziprasidone is sedating, and sage is an herbal product with reported mild sedative properties, so additive drowsiness is theoretically possible. Evidence for a meaningful clinical interaction is sparse.
What this interaction means in plain words
Sage and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive central nervous system depressant effects; the mechanism for sage is not firmly established.
What to do
Advise patients to note excess drowsiness and to avoid driving if sedated. Review use of herbal products at medication reviews.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Frequently asked questions
Can I take Sage with Ziprasidone?
MediHelp rates the interaction as minor. Sage and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ziprasidone is sedating, and sage is an herbal product with reported mild sedative properties, so additive drowsiness is theoretically possible. Evidence for a meaningful clinical interaction is sparse.
How serious is the interaction between Sage and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to note excess drowsiness and to avoid driving if sedated. Review use of herbal products at medication reviews.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
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