Drug interactions
Albuterol + Tacrolimus
Severity: Moderate
Albuterol and Tacrolimus: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can prolong the QTc interval, and albuterol may also cause hypokalemia. Combined use may modestly raise the risk of arrhythmia, especially with high-dose or nebulized beta-agonist use.
What this interaction means in plain words
Albuterol and Tacrolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia as a contributing factor.
What to do
Check potassium and magnesium and consider an ECG in patients with other QT risk factors. Use the lowest effective albuterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tacrolimus
- Adenovirus types 4 and 7 live + Tacrolimus Contraindicated
- Bcg vaccine live + Tacrolimus Contraindicated
- Cidofovir + Tacrolimus Contraindicated
- Cyclosporin + Tacrolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Tacrolimus Contraindicated
- Measles mumps and rubella vaccine live + Tacrolimus Contraindicated
Frequently asked questions
Can I take Albuterol with Tacrolimus?
MediHelp rates the interaction as moderate. Albuterol and Tacrolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QTc interval, and albuterol may also cause hypokalemia. Combined use may modestly raise the risk of arrhythmia, especially with high-dose or nebulized beta-agonist use.
How serious is the interaction between Albuterol and Tacrolimus?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and consider an ECG in patients with other QT risk factors. Use the lowest effective albuterol dose.
What other medicines interact with Tacrolimus?
MediHelp also lists interactions of Tacrolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Cidofovir. The full list is on the Tacrolimus page.
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