Drug reference
tacrolimus
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Immunosuppressants)
Mechanism of action
Calcineurin inhibitor; inhibits T-cell activation and proliferation, humoral immunity. Macrolide antibiotic; potent immunosuppressant
Common side effects
- Tremor
- Infection
- Hypertension
- Hypophosphatemia
- Increased creatinine
- Topical: Burning sensation
- Diarrhea
Known interactions (6)
- cidofovir + tacrolimus Contraindicated
- amphotericin b + tacrolimus Major
- dronedarone + tacrolimus Major
- fluconazole + tacrolimus Major
- tacrolimus + voriconazole Major
- hepatitis a vaccine inactivated + tacrolimus Moderate
Related conditions
Frequently asked questions
What drug class is tacrolimus?
tacrolimus belongs to: Miscellaneous.
How does tacrolimus work?
Calcineurin inhibitor; inhibits T-cell activation and proliferation, humoral immunity. Macrolide antibiotic; potent immunosuppressant
What are the common side effects of tacrolimus?
Tremor, Infection, Hypertension, Hypophosphatemia, Increased creatinine, Topical: Burning sensation, Diarrhea
Which drugs interact with tacrolimus?
cidofovir, amphotericin b, dronedarone, fluconazole, voriconazole, hepatitis a vaccine inactivated
Full monographs, dosing and an interaction checker in the MediHelp app
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