Drug interactions
Salbutamol + Voclosporin
Severity: Moderate
Salbutamol and Voclosporin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voclosporin can prolong the QT interval at supratherapeutic exposures. Salbutamol may add to the arrhythmic risk via hypokalemia and tachycardia.
What this interaction means in plain words
Salbutamol and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Salbutamol belongs to Respiratory; Voclosporin belongs to Miscellaneous.
Why it happens
Additive QT prolongation with beta-2 agonist-induced hypokalemia and sympathetic stimulation.
What to do
Monitor potassium and magnesium and consider an ECG in patients with other QT risk factors. Use the lowest effective salbutamol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Voclosporin
- Clarithromycin + Voclosporin Contraindicated
- Cyclosporin + Voclosporin Contraindicated
- Ensitrelvir + Voclosporin Contraindicated
- Itraconazole + Voclosporin Contraindicated
- Ketoconazole + Voclosporin Contraindicated
- Posaconazole + Voclosporin Contraindicated
Frequently asked questions
Can I take Salbutamol with Voclosporin?
MediHelp rates the interaction as moderate. Salbutamol and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voclosporin can prolong the QT interval at supratherapeutic exposures. Salbutamol may add to the arrhythmic risk via hypokalemia and tachycardia.
How serious is the interaction between Salbutamol and Voclosporin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and magnesium and consider an ECG in patients with other QT risk factors. Use the lowest effective salbutamol dose.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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