Drug interactions
Albuterol + Voriconazole
Severity: Moderate
Albuterol and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole prolongs the QT interval and albuterol can cause hypokalemia and tachycardia, which may add to arrhythmia risk. The clinical significance is generally modest at usual inhaled doses but higher with systemic or high-dose use.
What this interaction means in plain words
Albuterol and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QTc effects, with beta-agonist-induced hypokalemia facilitating arrhythmia.
What to do
Monitor potassium and ECG in patients with cardiac risk factors or on high-dose albuterol. Correct electrolyte abnormalities promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Albuterol with Voriconazole?
MediHelp rates the interaction as moderate. Albuterol and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voriconazole prolongs the QT interval and albuterol can cause hypokalemia and tachycardia, which may add to arrhythmia risk. The clinical significance is generally modest at usual inhaled doses but higher with systemic or high-dose use.
How serious is the interaction between Albuterol and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and ECG in patients with cardiac risk factors or on high-dose albuterol. Correct electrolyte abnormalities promptly.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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