Drug interactions
carbamazepine + voriconazole
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↓ voriconazole; ↑ CBZ toxicity; avoid/contraindicated.
Mechanism of action
CYP3A4 induction/inhibition bidirectional.
Clinical management
Avoid; choose alternative antifungal/anticonvulsant.
Drug reference
References
Frequently asked questions
Can I take carbamazepine with voriconazole?
The interaction is rated: Major. ↓ voriconazole; ↑ CBZ toxicity; avoid/contraindicated.
How serious is the interaction between carbamazepine and voriconazole?
The interaction is rated: Major. Evidence level: High.
How is the interaction between carbamazepine and voriconazole managed?
Avoid; choose alternative antifungal/anticonvulsant.
Why do carbamazepine and voriconazole interact?
CYP3A4 induction/inhibition bidirectional.
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