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Drug interactions

Shark cartilage + Tolazamide

Severity: Minor

Shark cartilage and Tolazamide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Shark cartilage supplements are theorized to add to the glucose-lowering effect of tolazamide. Clinical evidence is lacking, and product content varies.

What this interaction means in plain words

Shark cartilage and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

A possible additive effect on blood glucose has been proposed, but the mechanism is not established.

What to do

Counsel the patient to report use of the supplement and to monitor blood glucose for symptoms of hypoglycemia. No empirical dose change is needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Shark cartilage with Tolazamide?

MediHelp rates the interaction as minor. Shark cartilage and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage supplements are theorized to add to the glucose-lowering effect of tolazamide. Clinical evidence is lacking, and product content varies.

How serious is the interaction between Shark cartilage and Tolazamide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to report use of the supplement and to monitor blood glucose for symptoms of hypoglycemia. No empirical dose change is needed.

What other medicines interact with Tolazamide?

MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.

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