Drug interactions
Shark cartilage + Tolbutamide
Severity: Minor
Shark cartilage and Tolbutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shark cartilage has been suggested to affect blood glucose, so it might add to the effect of tolbutamide. Evidence is largely theoretical.
What this interaction means in plain words
Shark cartilage and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive glucose-lowering effect; mechanism not established.
What to do
Ask patients about supplement use and monitor blood glucose if shark cartilage is taken regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolbutamide
- Glyburide-metformin + Tolbutamide Major
- Insulin degludec-liraglutide + Tolbutamide Major
- Aceclofenac + Tolbutamide Moderate
- Acemetacin + Tolbutamide Moderate
- Acetylsalicylic acid + Tolbutamide Moderate
- Albiglutide + Tolbutamide Moderate
Frequently asked questions
Can I take Shark cartilage with Tolbutamide?
MediHelp rates the interaction as minor. Shark cartilage and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage has been suggested to affect blood glucose, so it might add to the effect of tolbutamide. Evidence is largely theoretical.
How serious is the interaction between Shark cartilage and Tolbutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about supplement use and monitor blood glucose if shark cartilage is taken regularly.
What other medicines interact with Tolbutamide?
MediHelp also lists interactions of Tolbutamide with, for example, Glyburide-metformin, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolbutamide page.
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