Drug interactions
Sodium sulfate / potassium sulfate / magnesium sulfate + Vardenafil
Severity: Minor
Sodium sulfate / potassium sulfate / magnesium sulfate and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Osmotic bowel preparations can cause fluid loss and electrolyte disturbances, which raise the risk of arrhythmia with QT-prolonging drugs such as vardenafil. The effect is mainly relevant in patients with heart disease or other risk factors.
What this interaction means in plain words
Sodium sulfate / potassium sulfate / magnesium sulfate and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Bowel preparation-induced electrolyte and volume shifts may add to the QT-prolonging effect of vardenafil.
What to do
Consider withholding vardenafil on the day of bowel preparation in patients with cardiac risk factors. Ensure adequate hydration and consider ECG in high-risk patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Sodium sulfate / potassium sulfate / magnesium sulfate with Vardenafil?
MediHelp rates the interaction as minor. Sodium sulfate / potassium sulfate / magnesium sulfate and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Osmotic bowel preparations can cause fluid loss and electrolyte disturbances, which raise the risk of arrhythmia with QT-prolonging drugs such as vardenafil. The effect is mainly relevant in patients with heart disease or other risk factors.
How serious is the interaction between Sodium sulfate / potassium sulfate / magnesium sulfate and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider withholding vardenafil on the day of bowel preparation in patients with cardiac risk factors. Ensure adequate hydration and consider ECG in high-risk patients.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.
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