Drug interactions
Sodium sulfate / potassium sulfate / magnesium sulfate + Verapamil
Severity: Moderate
Sodium sulfate / potassium sulfate / magnesium sulfate and Verapamil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium absorbed from this bowel preparation can add to the calcium channel blocking effect of verapamil, especially in patients with renal impairment or dehydration. Hypotension or muscle weakness may result.
What this interaction means in plain words
Sodium sulfate / potassium sulfate / magnesium sulfate and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive physiological antagonism of calcium-dependent cardiac and vascular smooth muscle function by magnesium and verapamil.
What to do
Maintain hydration and monitor blood pressure and muscle strength; check serum magnesium if renal function is reduced or symptoms develop.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Frequently asked questions
Can I take Sodium sulfate / potassium sulfate / magnesium sulfate with Verapamil?
MediHelp rates the interaction as moderate. Sodium sulfate / potassium sulfate / magnesium sulfate and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium absorbed from this bowel preparation can add to the calcium channel blocking effect of verapamil, especially in patients with renal impairment or dehydration. Hypotension or muscle weakness may result.
How serious is the interaction between Sodium sulfate / potassium sulfate / magnesium sulfate and Verapamil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Maintain hydration and monitor blood pressure and muscle strength; check serum magnesium if renal function is reduced or symptoms develop.
What other medicines interact with Verapamil?
MediHelp also lists interactions of Verapamil with, for example, Dofetilide, Flibanserin, Lomitapide. The full list is on the Verapamil page.
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