Drug interactions
Somatropin + Thioridazine
Severity: Minor
Somatropin and Thioridazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase the activity of some cytochrome P450 enzymes, which could lower levels of drugs cleared by them. The effect on thioridazine is theoretical and mainly relevant to CYP2D6/3A4 substrates.
What this interaction means in plain words
Somatropin and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Somatropin belongs to Endocrine; Thioridazine belongs to Central Nervous System.
Why it happens
Possible induction of CYP-mediated metabolism by somatropin; the effect on thioridazine is not established.
What to do
No routine action; monitor clinical response to thioridazine when somatropin is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Somatropin and Thioridazine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Other interactions of Somatropin
- Acarbose + Somatropin Moderate
- Albiglutide + Somatropin Moderate
- Alogliptin-metformin + Somatropin Moderate
- Alogliptin-pioglitazone + Somatropin Moderate
- Alogliptin + Somatropin Moderate
- Betamethasone + Somatropin Moderate
Frequently asked questions
Can I take Somatropin with Thioridazine?
MediHelp rates the interaction as minor. Somatropin and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase the activity of some cytochrome P450 enzymes, which could lower levels of drugs cleared by them. The effect on thioridazine is theoretical and mainly relevant to CYP2D6/3A4 substrates.
How serious is the interaction between Somatropin and Thioridazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; monitor clinical response to thioridazine when somatropin is started or stopped.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
