Drug interactions
Stavudine + Ublituximab
Severity: Moderate
Stavudine and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and increases infection risk, which is a concern in people with HIV. It does not alter stavudine pharmacology, so the legacy description of reduced stavudine effect is not accurate.
What this interaction means in plain words
Stavudine and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Stavudine belongs to Anti Virals; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from B-cell depletion in an immunocompromised host; no direct effect on stavudine exposure.
What to do
Check HIV viral load and CD4 count and screen for hepatitis B before ublituximab. Monitor for infections during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Stavudine
- Didanosine + Stavudine Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Stavudine Contraindicated
- Hydroxycarbamide + Stavudine Contraindicated
- Stavudine + Zidovudine Contraindicated
- Atidarsagene autotemcel + Stavudine Major
- Betibeglogene autotemcel + Stavudine Major
Other interactions of Ublituximab
Frequently asked questions
Can I take Stavudine with Ublituximab?
MediHelp rates the interaction as moderate. Stavudine and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ublituximab depletes B cells and increases infection risk, which is a concern in people with HIV. It does not alter stavudine pharmacology, so the legacy description of reduced stavudine effect is not accurate.
How serious is the interaction between Stavudine and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check HIV viral load and CD4 count and screen for hepatitis B before ublituximab. Monitor for infections during therapy.
What other medicines interact with Stavudine?
MediHelp also lists interactions of Stavudine with, for example, Didanosine, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Hydroxycarbamide. The full list is on the Stavudine page.
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