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Drug interactions

Stevia + Tolazamide

Severity: Minor

Stevia and Tolazamide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Stevia sweeteners may modestly lower blood glucose, so a small additive effect with a sulfonylurea is possible. Clinically significant hypoglycemia is unlikely at dietary intakes.

What this interaction means in plain words

Stevia and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible enhancement of insulin secretion and glucose lowering; the mechanism is not firmly established.

What to do

No dose change is needed for dietary use. Check blood glucose if large amounts of stevia products are taken.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Stevia with Tolazamide?

MediHelp rates the interaction as minor. Stevia and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stevia sweeteners may modestly lower blood glucose, so a small additive effect with a sulfonylurea is possible. Clinically significant hypoglycemia is unlikely at dietary intakes.

How serious is the interaction between Stevia and Tolazamide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed for dietary use. Check blood glucose if large amounts of stevia products are taken.

What other medicines interact with Tolazamide?

MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.

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