Drug interactions
Sunitinib + Telavancin
Severity: Moderate
Sunitinib and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sunitinib is labeled with a warning for QT prolongation and torsades de pointes, and telavancin may add to the effect. The combination may increase the risk of serious arrhythmia.
What this interaction means in plain words
Sunitinib and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Sunitinib belongs to Oncology; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QTc prolongation.
What to do
Obtain a baseline ECG and correct potassium and magnesium. Monitor the QTc during combined therapy and consider an alternative antibacterial if it rises markedly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Frequently asked questions
Can I take Sunitinib with Telavancin?
MediHelp rates the interaction as moderate. Sunitinib and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sunitinib is labeled with a warning for QT prolongation and torsades de pointes, and telavancin may add to the effect. The combination may increase the risk of serious arrhythmia.
How serious is the interaction between Sunitinib and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct potassium and magnesium. Monitor the QTc during combined therapy and consider an alternative antibacterial if it rises markedly.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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