Drug interactions
Telmisartan + Treprostinil
Severity: Moderate
Telmisartan and Treprostinil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a vasodilator, and added to telmisartan it can enhance blood pressure lowering. Symptomatic hypotension or dizziness may result, especially when starting or increasing doses.
What this interaction means in plain words
Telmisartan and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Telmisartan belongs to Cardiovascular; Treprostinil belongs to Cardiovascular.
Why it happens
Additive vasodilatory effects of prostacyclin receptor agonism and angiotensin receptor blockade.
What to do
Monitor blood pressure when starting or titrating treprostinil. Lower the telmisartan dose if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Treprostinil
Frequently asked questions
Can I take Telmisartan with Treprostinil?
MediHelp rates the interaction as moderate. Telmisartan and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Treprostinil is a vasodilator, and added to telmisartan it can enhance blood pressure lowering. Symptomatic hypotension or dizziness may result, especially when starting or increasing doses.
How serious is the interaction between Telmisartan and Treprostinil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when starting or titrating treprostinil. Lower the telmisartan dose if hypotension develops.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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