Drug interactions
Tetanus toxoid adsorbed or fluid + Ustekinumab
Severity: Minor
Tetanus toxoid adsorbed or fluid and Ustekinumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetanus toxoid is non-live and safe with ustekinumab. Any effect on antibody response is expected to be small.
What this interaction means in plain words
Tetanus toxoid adsorbed or fluid and Ustekinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic: IL-12/23 inhibition may slightly reduce vaccine responses; not well characterized for toxoids.
What to do
Vaccinate or boost per schedule, including for wound management; no change to ustekinumab is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ustekinumab
- Bcg vaccine live + Ustekinumab Contraindicated
- Typhoid vaccine live + Ustekinumab Contraindicated
- Adalimumab + Ustekinumab Major
- Adenovirus types 4 and 7 live + Ustekinumab Major
- Alefacept + Ustekinumab Major
- Anakinra + Ustekinumab Major
Frequently asked questions
Can I take Tetanus toxoid adsorbed or fluid with Ustekinumab?
MediHelp rates the interaction as minor. Tetanus toxoid adsorbed or fluid and Ustekinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetanus toxoid is non-live and safe with ustekinumab. Any effect on antibody response is expected to be small.
How serious is the interaction between Tetanus toxoid adsorbed or fluid and Ustekinumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate or boost per schedule, including for wound management; no change to ustekinumab is needed.
What other medicines interact with Ustekinumab?
MediHelp also lists interactions of Ustekinumab with, for example, Bcg vaccine live, Typhoid vaccine live, Adalimumab. The full list is on the Ustekinumab page.
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