Drug interactions
Tolazamide + Vanadium
Severity: Minor
Tolazamide and Vanadium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vanadium compounds have insulin-mimetic activity and may lower blood glucose, so they could add to the effect of a sulfonylurea. Human data are limited and the clinical significance is unclear.
What this interaction means in plain words
Tolazamide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Insulin-mimetic effects of vanadium may add to the glucose-lowering action of tolazamide.
What to do
Monitor blood glucose when vanadium supplements are started or stopped. Reduce the tolazamide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Frequently asked questions
Can I take Tolazamide with Vanadium?
MediHelp rates the interaction as minor. Tolazamide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vanadium compounds have insulin-mimetic activity and may lower blood glucose, so they could add to the effect of a sulfonylurea. Human data are limited and the clinical significance is unclear.
How serious is the interaction between Tolazamide and Vanadium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when vanadium supplements are started or stopped. Reduce the tolazamide dose if hypoglycemia occurs.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
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