Drug interactions
Triamcinolone acetonide injectable + Verapamil
Severity: Moderate
Triamcinolone acetonide injectable and Verapamil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Verapamil may increase systemic exposure to triamcinolone, which is metabolized by CYP3A4. This could cause corticosteroid excess such as Cushingoid features or adrenal suppression, mainly with repeated dosing.
What this interaction means in plain words
Triamcinolone acetonide injectable and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
CYP3A4 inhibition by verapamil slows triamcinolone clearance.
What to do
Watch for signs of corticosteroid excess with repeated injections, and consider limiting the dose or frequency of triamcinolone.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Frequently asked questions
Can I take Triamcinolone acetonide injectable with Verapamil?
MediHelp rates the interaction as moderate. Triamcinolone acetonide injectable and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Verapamil may increase systemic exposure to triamcinolone, which is metabolized by CYP3A4. This could cause corticosteroid excess such as Cushingoid features or adrenal suppression, mainly with repeated dosing.
How serious is the interaction between Triamcinolone acetonide injectable and Verapamil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Watch for signs of corticosteroid excess with repeated injections, and consider limiting the dose or frequency of triamcinolone.
What other medicines interact with Verapamil?
MediHelp also lists interactions of Verapamil with, for example, Dofetilide, Flibanserin, Lomitapide. The full list is on the Verapamil page.
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