Drug interactions
Valganciclovir + Vincristine
Severity: Minor
Valganciclovir and Vincristine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valganciclovir (via ganciclovir) can cause bone marrow suppression, and vincristine may add some hematologic toxicity, although vincristine is relatively marrow-sparing. Combined use may increase the risk of cytopenias in vulnerable patients.
What this interaction means in plain words
Valganciclovir and Vincristine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Valganciclovir belongs to Anti Virals; Vincristine belongs to Oncology.
Why it happens
Possible additive hematologic toxicity; mechanism not firmly established for vincristine.
What to do
Monitor complete blood counts during co-therapy and adjust valganciclovir or chemotherapy if significant cytopenias occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Valganciclovir
Other interactions of Vincristine
- Adenovirus types 4 and 7 live + Vincristine Contraindicated
- Apalutamide + Vincristine Major
- Atazanavir + Vincristine Major
- Ceritinib + Vincristine Major
- Chloramphenicol + Vincristine Major
- Clarithromycin + Vincristine Major
Frequently asked questions
Can I take Valganciclovir with Vincristine?
MediHelp rates the interaction as minor. Valganciclovir and Vincristine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Valganciclovir (via ganciclovir) can cause bone marrow suppression, and vincristine may add some hematologic toxicity, although vincristine is relatively marrow-sparing. Combined use may increase the risk of cytopenias in vulnerable patients.
How serious is the interaction between Valganciclovir and Vincristine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts during co-therapy and adjust valganciclovir or chemotherapy if significant cytopenias occur.
What other medicines interact with Valganciclovir?
MediHelp also lists interactions of Valganciclovir with, for example, Didanosine, Ganciclovir, Liposomal doxorubicin. The full list is on the Valganciclovir page.
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