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Abobotulinumtoxina + Atropine

شدت: متوسط

Abobotulinumtoxina and Atropine: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Anticholinergic drugs such as atropine may add to the effects of botulinum toxin, which blocks acetylcholine release. This can increase systemic anticholinergic effects such as dry mouth, blurred vision and urinary retention, and may increase muscle weakness.

معنای این تداخل به زبان ساده

Abobotulinumtoxina and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

سطح شواهد: Low

چرا رخ می‌دهد

Additive anticholinergic effects at cholinergic synapses combined with presynaptic blockade of acetylcholine release by the toxin.

اقدام لازم

Monitor for excessive weakness, swallowing or breathing difficulty and anticholinergic symptoms after injection. Avoid unnecessary additional anticholinergics around the time of treatment.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Abobotulinumtoxina و Atropine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Abobotulinumtoxina with Atropine?

MediHelp rates the interaction as moderate. Abobotulinumtoxina and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anticholinergic drugs such as atropine may add to the effects of botulinum toxin, which blocks acetylcholine release. This can increase systemic anticholinergic effects such as dry mouth, blurred vision and urinary retention, and may increase muscle weakness.

How serious is the interaction between Abobotulinumtoxina and Atropine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive weakness, swallowing or breathing difficulty and anticholinergic symptoms after injection. Avoid unnecessary additional anticholinergics around the time of treatment.

What other medicines interact with Atropine?

MediHelp also lists interactions of Atropine with, for example, Eluxadoline, Henbane, Pramlintide. The full list is on the Atropine page.

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