تداخل‌های دارویی
Acetylsalicylic acid + Prasugrel
شدت: شدید
Acetylsalicylic acid and Prasugrel: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Aspirin and prasugrel are combined deliberately in acute coronary syndrome and after stenting, but together they substantially increase the risk of major and fatal bleeding. Risk is higher in elderly patients, those with low body weight, or with prior stroke.
معنای این تداخل به زبان ساده
Acetylsalicylic acid and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acetylsalicylic acid belongs to Musculoskeletal; Prasugrel belongs to Cardiovascular.
چرا رخ می‌دهد
Additive platelet inhibition through irreversible COX-1 blockade (aspirin) and irreversible P2Y12 receptor blockade (prasugrel).
اقدام لازم
Use only when indicated, keep aspirin at low maintenance dose, and monitor for bleeding and hemoglobin; limit duration according to guidelines and consider alternatives in high-bleeding-risk patients.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Acetylsalicylic acid و Prasugrel، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Acetylsalicylic acid
تداخلات دیگر Prasugrel
پرسش‌های متداول
Can I take Acetylsalicylic acid with Prasugrel?
MediHelp rates the interaction as major. Acetylsalicylic acid and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Aspirin and prasugrel are combined deliberately in acute coronary syndrome and after stenting, but together they substantially increase the risk of major and fatal bleeding. Risk is higher in elderly patients, those with low body weight, or with prior stroke.
How serious is the interaction between Acetylsalicylic acid and Prasugrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when indicated, keep aspirin at low maintenance dose, and monitor for bleeding and hemoglobin; limit duration according to guidelines and consider alternatives in high-bleeding-risk patients.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
