تداخل‌های دارویی
Cangrelor + Prasugrel
شدت: شدید
Cangrelor and Prasugrel: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Cangrelor reversibly blocks the platelet P2Y12 receptor and can prevent the active metabolite of prasugrel from binding if given during the infusion. This results in loss of the intended antiplatelet effect of prasugrel and a risk of stent thrombosis.
معنای این تداخل به زبان ساده
Cangrelor and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cangrelor belongs to Cardiovascular; Prasugrel belongs to Cardiovascular.
چرا رخ می‌دهد
Competition at the P2Y12 receptor, where cangrelor occupies the binding site and blocks the irreversible binding of prasugrel's active metabolite.
اقدام لازم
Give prasugrel only after the cangrelor infusion has been discontinued, not during it.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cangrelor و Prasugrel، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cangrelor
- Cangrelor + Clopidogrel شدید
- Cangrelor + Warfarin متوسط
تداخلات دیگر Prasugrel
پرسش‌های متداول
Can I take Cangrelor with Prasugrel?
MediHelp rates the interaction as major. Cangrelor and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cangrelor reversibly blocks the platelet P2Y12 receptor and can prevent the active metabolite of prasugrel from binding if given during the infusion. This results in loss of the intended antiplatelet effect of prasugrel and a risk of stent thrombosis.
How serious is the interaction between Cangrelor and Prasugrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give prasugrel only after the cangrelor infusion has been discontinued, not during it.
What other medicines interact with Cangrelor?
MediHelp also lists interactions of Cangrelor with, for example, Clopidogrel, Warfarin. The full list is on the Cangrelor page.
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مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
