تداخل‌های دارویی
Aluminum hydroxide + Penicillamine
شدت: متوسط
Aluminum hydroxide and Penicillamine: moderate interaction.
آخرین به‌روزرسانی
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خلاصه
Aluminum-containing antacids reduce the absorption of penicillamine, which can lower its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis. The effect is clinically relevant when doses are close together.
معنای این تداخل به زبان ساده
Aluminum hydroxide and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
چرا رخ می‌دهد
Aluminum chelates or adsorbs penicillamine in the gut, reducing its oral absorption.
اقدام لازم
Separate penicillamine and the antacid by at least 2 hours. Monitor clinical response, such as urinary copper or cystine, if antacids are used regularly.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Aluminum hydroxide و Penicillamine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Aluminum hydroxide
تداخلات دیگر Penicillamine
پرسش‌های متداول
Can I take Aluminum hydroxide with Penicillamine?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum-containing antacids reduce the absorption of penicillamine, which can lower its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis. The effect is clinically relevant when doses are close together.
How serious is the interaction between Aluminum hydroxide and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate penicillamine and the antacid by at least 2 hours. Monitor clinical response, such as urinary copper or cystine, if antacids are used regularly.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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