تداخل‌های دارویی
Amlodipine-olmesartan + Canagliflozin
شدت: متوسط
Amlodipine-olmesartan and Canagliflozin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Canagliflozin can cause volume depletion and hypotension, and with olmesartan may increase the risk of acute kidney injury. Canagliflozin has been associated with small rises in potassium, mainly in renally impaired patients taking RAAS inhibitors.
معنای این تداخل به زبان ساده
Amlodipine-olmesartan and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan belongs to Cardiovascular; Canagliflozin belongs to Endocrine.
چرا رخ می‌دهد
Additive effects of osmotic diuresis and renin-angiotensin blockade on volume status and renal hemodynamics.
اقدام لازم
Assess volume status and renal function before starting canagliflozin and monitor creatinine, potassium and blood pressure afterward. Reduce antihypertensive or diuretic doses if hypotension occurs.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Amlodipine-olmesartan و Canagliflozin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Amlodipine-olmesartan
تداخلات دیگر Canagliflozin
پرسش‌های متداول
Can I take Amlodipine-olmesartan with Canagliflozin?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Canagliflozin can cause volume depletion and hypotension, and with olmesartan may increase the risk of acute kidney injury. Canagliflozin has been associated with small rises in potassium, mainly in renally impaired patients taking RAAS inhibitors.
How serious is the interaction between Amlodipine-olmesartan and Canagliflozin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess volume status and renal function before starting canagliflozin and monitor creatinine, potassium and blood pressure afterward. Reduce antihypertensive or diuretic doses if hypotension occurs.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
