تداخل‌های دارویی
Amlodipine-olmesartan-hydrochlorothiazide + Canagliflozin
شدت: متوسط
Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Canagliflozin causes osmotic diuresis and can add to the volume depletion and blood pressure lowering of an ARB and thiazide, with a risk of hypotension and acute kidney injury. Canagliflozin may also modestly increase potassium in some patients, especially with an ARB and renal impairment.
معنای این تداخل به زبان ساده
Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Canagliflozin belongs to Endocrine.
چرا رخ می‌دهد
Additive diuretic and hypotensive effects, with possible additive effects on potassium and renal hemodynamics.
اقدام لازم
Assess volume status before starting canagliflozin and consider reducing the diuretic dose. Monitor blood pressure, renal function and potassium.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Amlodipine-olmesartan-hydrochlorothiazide و Canagliflozin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide منع مصرف
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide منع مصرف
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan منع مصرف
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide شدید
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide شدید
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide شدید
تداخلات دیگر Canagliflozin
پرسش‌های متداول
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Canagliflozin?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Canagliflozin causes osmotic diuresis and can add to the volume depletion and blood pressure lowering of an ARB and thiazide, with a risk of hypotension and acute kidney injury. Canagliflozin may also modestly increase potassium in some patients, especially with an ARB and renal impairment.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess volume status before starting canagliflozin and consider reducing the diuretic dose. Monitor blood pressure, renal function and potassium.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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