تداخل‌های دارویی
Atidarsagene autotemcel + Dolutegravir
شدت: شدید
Atidarsagene autotemcel and Dolutegravir: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Antiretroviral drugs can interfere with manufacture of this lentiviral gene therapy by inhibiting transduction. Dolutegravir, an integrase inhibitor, may compromise product quality if present at apheresis.
معنای این تداخل به زبان ساده
Atidarsagene autotemcel and Dolutegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Atidarsagene autotemcel belongs to Miscellaneous; Dolutegravir belongs to Anti Virals.
چرا رخ می‌دهد
Antiretroviral activity inhibits lentiviral vector transduction of harvested cells.
اقدام لازم
Stop dolutegravir at least one month before mobilization, allowing for elimination, and keep it off through apheresis. Arrange interim HIV management with specialists.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atidarsagene autotemcel و Dolutegravir، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dolutegravir
تداخلات دیگر Atidarsagene autotemcel
پرسش‌های متداول
Can I take Atidarsagene autotemcel with Dolutegravir?
MediHelp rates the interaction as major. Atidarsagene autotemcel and Dolutegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antiretroviral drugs can interfere with manufacture of this lentiviral gene therapy by inhibiting transduction. Dolutegravir, an integrase inhibitor, may compromise product quality if present at apheresis.
How serious is the interaction between Atidarsagene autotemcel and Dolutegravir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop dolutegravir at least one month before mobilization, allowing for elimination, and keep it off through apheresis. Arrange interim HIV management with specialists.
What other medicines interact with Dolutegravir?
MediHelp also lists interactions of Dolutegravir with, for example, Dofetilide, Aluminum hydroxide, Betibeglogene autotemcel. The full list is on the Dolutegravir page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
