تداخلهای دارویی
Atidarsagene autotemcel + Didanosine
شدت: شدید
Atidarsagene autotemcel and Didanosine: major interaction.
آخرین بهروزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصهای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمیشود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Antiretrovirals may impair lentiviral transduction of the patient's collected hematopoietic cells and so interfere with manufacture of the gene therapy. This could reduce the product's effectiveness.
معنای این تداخل به زبان ساده
Atidarsagene autotemcel and Didanosine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Atidarsagene autotemcel belongs to Miscellaneous; Didanosine belongs to Anti Virals.
چرا رخ میدهد
Reverse transcriptase inhibitors can interfere with lentiviral vector transduction during cell manufacturing.
اقدام لازم
Stop didanosine at least 1 month before cell mobilization, or longer to allow for elimination, and keep it off through apheresis. Arrange alternative HIV management with a specialist.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Atidarsagene autotemcel و Didanosine، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Didanosine
- Didanosine + Elvitegravir / cobicistat / emtricitabine / tenofovir df منع مصرف
- Didanosine + Hydroxycarbamide منع مصرف
- Didanosine + Hydroxyurea منع مصرف
- Didanosine + Ribavirin منع مصرف
- Didanosine + Stavudine منع مصرف
- Allopurinol + Didanosine شدید
تداخلات دیگر Atidarsagene autotemcel
پرسشهای متداول
Can I take Atidarsagene autotemcel with Didanosine?
MediHelp rates the interaction as major. Atidarsagene autotemcel and Didanosine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antiretrovirals may impair lentiviral transduction of the patient's collected hematopoietic cells and so interfere with manufacture of the gene therapy. This could reduce the product's effectiveness.
How serious is the interaction between Atidarsagene autotemcel and Didanosine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop didanosine at least 1 month before cell mobilization, or longer to allow for elimination, and keep it off through apheresis. Arrange alternative HIV management with a specialist.
What other medicines interact with Didanosine?
MediHelp also lists interactions of Didanosine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Hydroxycarbamide, Hydroxyurea. The full list is on the Didanosine page.
تکنگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.