تداخل‌های دارویی
Atidarsagene autotemcel + Raltegravir
شدت: شدید
Atidarsagene autotemcel and Raltegravir: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Antiretroviral drugs can interfere with the manufacture of this lentiviral gene therapy by inhibiting transduction of mobilized cells. Raltegravir, an integrase inhibitor, may reduce the efficiency of vector integration.
معنای این تداخل به زبان ساده
Atidarsagene autotemcel and Raltegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Atidarsagene autotemcel belongs to Miscellaneous; Raltegravir belongs to Anti Virals.
چرا رخ می‌دهد
Antiretrovirals inhibit lentiviral vector transduction of harvested stem cells during manufacturing.
اقدام لازم
Stop raltegravir at least one month before mobilization, or longer to cover drug elimination, and keep it off through apheresis. Arrange alternative HIV management with the treating team.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atidarsagene autotemcel و Raltegravir، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Raltegravir
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Raltegravir منع مصرف
- Aluminum hydroxide / magnesium carbonate + Raltegravir شدید
- Aluminum hydroxide / magnesium trisilicate + Raltegravir شدید
- Aluminum hydroxide + Raltegravir شدید
- Betibeglogene autotemcel + Raltegravir شدید
- Cabotegravir + Raltegravir شدید
تداخلات دیگر Atidarsagene autotemcel
پرسش‌های متداول
Can I take Atidarsagene autotemcel with Raltegravir?
MediHelp rates the interaction as major. Atidarsagene autotemcel and Raltegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antiretroviral drugs can interfere with the manufacture of this lentiviral gene therapy by inhibiting transduction of mobilized cells. Raltegravir, an integrase inhibitor, may reduce the efficiency of vector integration.
How serious is the interaction between Atidarsagene autotemcel and Raltegravir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop raltegravir at least one month before mobilization, or longer to cover drug elimination, and keep it off through apheresis. Arrange alternative HIV management with the treating team.
What other medicines interact with Raltegravir?
MediHelp also lists interactions of Raltegravir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Raltegravir page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
