تداخل‌های دارویی
Atidarsagene autotemcel + Tenofovir disoproxil
شدت: شدید
Atidarsagene autotemcel and Tenofovir disoproxil: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Antiretrovirals can interfere with the manufacture of gene-modified autologous cell products by inhibiting lentiviral transduction. Tenofovir taken before and during cell collection may reduce the quality of the product.
معنای این تداخل به زبان ساده
Atidarsagene autotemcel and Tenofovir disoproxil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Antiretroviral inhibition of lentiviral vector transduction of harvested cells during manufacturing.
اقدام لازم
Stop antiretrovirals for at least one month, or longer for long-acting agents, before cell mobilization and until apheresis is complete. Coordinate with the HIV specialist on management of the interruption.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atidarsagene autotemcel و Tenofovir disoproxil، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Atidarsagene autotemcel
پرسش‌های متداول
Can I take Atidarsagene autotemcel with Tenofovir disoproxil?
MediHelp rates the interaction as major. Atidarsagene autotemcel and Tenofovir disoproxil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antiretrovirals can interfere with the manufacture of gene-modified autologous cell products by inhibiting lentiviral transduction. Tenofovir taken before and during cell collection may reduce the quality of the product.
How serious is the interaction between Atidarsagene autotemcel and Tenofovir disoproxil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop antiretrovirals for at least one month, or longer for long-acting agents, before cell mobilization and until apheresis is complete. Coordinate with the HIV specialist on management of the interruption.
What other medicines interact with Atidarsagene autotemcel?
MediHelp also lists interactions of Atidarsagene autotemcel with, for example, Didanosine, Dolutegravir, Efavirenz. The full list is on the Atidarsagene autotemcel page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
