تداخل‌های دارویی
Atracurium + Corticotropin
شدت: متوسط
Atracurium and Corticotropin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Corticotropin stimulates endogenous corticosteroid release, and corticosteroids given with nondepolarizing neuromuscular blockers have been linked to acute quadriplegic myopathy, especially in critically ill patients on prolonged infusions. Risk is greatest with prolonged ventilation and high steroid exposure.
معنای این تداخل به زبان ساده
Atracurium and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atracurium belongs to Musculoskeletal; Corticotropin belongs to Endocrine.
چرا رخ می‌دهد
Additive muscle toxicity from corticosteroid-induced myopathy and prolonged neuromuscular blockade; the exact mechanism is not fully established.
اقدام لازم
Limit the duration and dose of neuromuscular blockade in patients receiving corticotropin, and monitor for persistent weakness and creatine kinase elevation.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atracurium و Corticotropin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Atracurium
تداخلات دیگر Corticotropin
پرسش‌های متداول
Can I take Atracurium with Corticotropin?
MediHelp rates the interaction as moderate. Atracurium and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticotropin stimulates endogenous corticosteroid release, and corticosteroids given with nondepolarizing neuromuscular blockers have been linked to acute quadriplegic myopathy, especially in critically ill patients on prolonged infusions. Risk is greatest with prolonged ventilation and high steroid exposure.
How serious is the interaction between Atracurium and Corticotropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit the duration and dose of neuromuscular blockade in patients receiving corticotropin, and monitor for persistent weakness and creatine kinase elevation.
What other medicines interact with Atracurium?
MediHelp also lists interactions of Atracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Atracurium page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
