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Atropine + Dicyclomine

شدت: متوسط

Atropine and Dicyclomine: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.

معنای این تداخل به زبان ساده

Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Atropine belongs to Miscellaneous; Dicyclomine belongs to Respiratory.

سطح شواهد: Moderate

چرا رخ می‌دهد

Additive blockade of muscarinic acetylcholine receptors.

اقدام لازم

Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atropine و Dicyclomine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Atropine with Dicyclomine?

MediHelp rates the interaction as moderate. Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.

How serious is the interaction between Atropine and Dicyclomine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

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