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تداخل‌های دارویی

Azathioprine + Bcg vaccine live

شدت: منع مصرف

Azathioprine and Bcg vaccine live: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

BCG is a live attenuated bacterial vaccine and can cause disseminated BCG infection in immunosuppressed patients. Azathioprine impairs the cellular immunity needed to contain it.

معنای این تداخل به زبان ساده

Azathioprine and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Moderate

چرا رخ می‌دهد

Azathioprine-induced suppression of T-cell function allows uncontrolled replication of live attenuated Mycobacterium bovis.

اقدام لازم

Do not give BCG to patients on azathioprine; defer until immunosuppression has been stopped for the interval recommended by local guidance. Assess tuberculosis risk by alternative means.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Azathioprine و Bcg vaccine live، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Azathioprine with Bcg vaccine live?

MediHelp rates the interaction as contraindicated. Azathioprine and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated bacterial vaccine and can cause disseminated BCG infection in immunosuppressed patients. Azathioprine impairs the cellular immunity needed to contain it.

How serious is the interaction between Azathioprine and Bcg vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients on azathioprine; defer until immunosuppression has been stopped for the interval recommended by local guidance. Assess tuberculosis risk by alternative means.

What other medicines interact with Azathioprine?

MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Febuxostat, Influenza virus vaccine quadrivalent intranasal. The full list is on the Azathioprine page.

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