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تداخل‌های دارویی

Azathioprine + Influenza virus vaccine quadrivalent intranasal

شدت: منع مصرف

Azathioprine and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by azathioprine. This creates a risk of vaccine-strain infection, and the vaccine response may also be reduced.

معنای این تداخل به زبان ساده

Azathioprine and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Moderate

چرا رخ می‌دهد

Azathioprine-induced impairment of cellular immunity may allow uncontrolled replication of live attenuated virus.

اقدام لازم

Do not use the live intranasal vaccine in patients on azathioprine. Give an inactivated injectable influenza vaccine instead.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Azathioprine و Influenza virus vaccine quadrivalent intranasal، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Azathioprine with Influenza virus vaccine quadrivalent intranasal?

MediHelp rates the interaction as contraindicated. Azathioprine and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by azathioprine. This creates a risk of vaccine-strain infection, and the vaccine response may also be reduced.

How serious is the interaction between Azathioprine and Influenza virus vaccine quadrivalent intranasal?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use the live intranasal vaccine in patients on azathioprine. Give an inactivated injectable influenza vaccine instead.

What other medicines interact with Azathioprine?

MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.

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