Balsalazide + Varicella virus vaccine live

MediHelp rates the interaction as major. Balsalazide and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Balsalazide is converted to mesalamine, a salicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. The risk is largely theoretical given balsalazide's low systemic salicylate exposure, but it is a labeled caution.

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.

MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Aceclofenac, Celecoxib. The full list is on the Balsalazide page.