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Balsalazide + Mesalamine

شدت: متوسط

Balsalazide and Mesalamine: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Balsalazide is a prodrug of mesalamine, so the two are the same active moiety and using both is therapeutic duplication. Combined use would increase mesalamine exposure and the risk of adverse effects such as renal impairment and mesalamine intolerance.

معنای این تداخل به زبان ساده

Balsalazide and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Balsalazide belongs to Gastrointestinal Tract; Mesalamine belongs to Gastrointestinal Tract.

سطح شواهد: Moderate

چرا رخ می‌دهد

Duplicate therapy: balsalazide is converted to mesalamine, giving additive exposure to the same active drug.

اقدام لازم

Avoid routine co-prescription; if combined for refractory disease, monitor renal function and watch for mesalamine adverse effects.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Balsalazide و Mesalamine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Balsalazide with Mesalamine?

MediHelp rates the interaction as moderate. Balsalazide and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Balsalazide is a prodrug of mesalamine, so the two are the same active moiety and using both is therapeutic duplication. Combined use would increase mesalamine exposure and the risk of adverse effects such as renal impairment and mesalamine intolerance.

How serious is the interaction between Balsalazide and Mesalamine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine co-prescription; if combined for refractory disease, monitor renal function and watch for mesalamine adverse effects.

What other medicines interact with Balsalazide?

MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.

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