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Balsalazide + Celecoxib

شدت: متوسط

Balsalazide and Celecoxib: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.

معنای این تداخل به زبان ساده

Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Balsalazide belongs to Gastrointestinal Tract; Celecoxib belongs to Musculoskeletal.

سطح شواهد: Low

چرا رخ می‌دهد

Additive nephrotoxic potential from NSAID-mediated prostaglandin inhibition and rare mesalamine-related interstitial nephritis.

اقدام لازم

Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Balsalazide و Celecoxib، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Balsalazide with Celecoxib?

MediHelp rates the interaction as moderate. Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.

How serious is the interaction between Balsalazide and Celecoxib?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.

What other medicines interact with Balsalazide?

MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.

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