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تداخل‌های دارویی

Balstilimab + Cefalexin

شدت: متوسط

Balstilimab and Cefalexin: moderate interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Observational data suggest that antibiotic exposure around the start of checkpoint inhibitor therapy may be associated with poorer outcomes, possibly through disruption of the gut microbiome. The association is not proven to be causal and is based on retrospective data.

معنای این تداخل به زبان ساده

Balstilimab and Cefalexin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

سطح شواهد: Low

چرا رخ می‌دهد

Antibiotic-induced gut dysbiosis may alter systemic immune responses to checkpoint blockade, but the mechanism is not established.

اقدام لازم

Prescribe antibiotics only when clearly indicated and use the shortest effective course. Do not withhold needed antibiotic treatment; monitor oncologic response.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Balstilimab و Cefalexin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Balstilimab with Cefalexin?

MediHelp rates the interaction as moderate. Balstilimab and Cefalexin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Observational data suggest that antibiotic exposure around the start of checkpoint inhibitor therapy may be associated with poorer outcomes, possibly through disruption of the gut microbiome. The association is not proven to be causal and is based on retrospective data.

How serious is the interaction between Balstilimab and Cefalexin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prescribe antibiotics only when clearly indicated and use the shortest effective course. Do not withhold needed antibiotic treatment; monitor oncologic response.

What other medicines interact with Cefalexin?

MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Bcg vaccine live. The full list is on the Cefalexin page.

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