تداخل‌های دارویی
Cefalexin + Kanamycin
شدت: متوسط
Cefalexin and Kanamycin: moderate interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Concurrent use of cefalexin with an aminoglycoside such as kanamycin has been associated with an increased risk of kidney injury in some reports. Aminoglycosides themselves are nephrotoxic and ototoxic, so any added renal impairment can raise drug exposure and toxicity.
معنای این تداخل به زبان ساده
Cefalexin and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
چرا رخ می‌دهد
Additive nephrotoxic potential, with reduced renal function leading to higher aminoglycoside accumulation and ototoxicity risk.
اقدام لازم
Monitor serum creatinine and urine output, and measure aminoglycoside levels where applicable. Adjust the kanamycin dose to renal function and report hearing or balance changes promptly.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefalexin و Kanamycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cefalexin
- Amikacin + Cefalexin متوسط
- Avelumab + Cefalexin متوسط
- Balstilimab + Cefalexin متوسط
- Bcg vaccine live + Cefalexin متوسط
- Cefalexin + Cholera vaccine متوسط
- Cefalexin + Gentamicin متوسط
پرسش‌های متداول
Can I take Cefalexin with Kanamycin?
MediHelp rates the interaction as moderate. Cefalexin and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Concurrent use of cefalexin with an aminoglycoside such as kanamycin has been associated with an increased risk of kidney injury in some reports. Aminoglycosides themselves are nephrotoxic and ototoxic, so any added renal impairment can raise drug exposure and toxicity.
How serious is the interaction between Cefalexin and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output, and measure aminoglycoside levels where applicable. Adjust the kanamycin dose to renal function and report hearing or balance changes promptly.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
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