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Cefalexin + Gentamicin

شدت: متوسط

Cefalexin and Gentamicin: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Gentamicin is nephrotoxic and ototoxic, and cephalosporins have been reported to add to renal injury in some patients. Cefalexin is rarely nephrotoxic, so the effect is modest. Risk rises with renal impairment, advanced age, and dehydration.

معنای این تداخل به زبان ساده

Cefalexin and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefalexin belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.

سطح شواهد: Low

چرا رخ می‌دهد

Possible additive nephrotoxicity; mechanism poorly defined.

اقدام لازم

Monitor serum creatinine and gentamicin levels during therapy. Maintain hydration and avoid additional nephrotoxins.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefalexin و Gentamicin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Cefalexin with Gentamicin?

MediHelp rates the interaction as moderate. Cefalexin and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gentamicin is nephrotoxic and ototoxic, and cephalosporins have been reported to add to renal injury in some patients. Cefalexin is rarely nephrotoxic, so the effect is modest. Risk rises with renal impairment, advanced age, and dehydration.

How serious is the interaction between Cefalexin and Gentamicin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and gentamicin levels during therapy. Maintain hydration and avoid additional nephrotoxins.

What other medicines interact with Cefalexin?

MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.

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